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牛白藤化学成分、药理作用及临床应用研究

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牛白藤[Hedyotis hedyotidea(DC。)Merr。]为茜草科耳草属干燥全草,在我国广西、广东、福建、台湾、贵州、云南等地广泛分布,资源丰富。现代研究表明,牛白藤中含有萜类、甾体类、香豆素类、木脂素类等化合物,具有镇痛、抗肿瘤、抗菌消炎、抗白血病效应等作用。目前,牛白藤的药理活性研究大多以萜类为主,但是相关的药理机制研究较少。因此,本文对牛白藤的化学成分与药理作用及临床应用研究进行归纳总结,为今后对牛白藤的开发利用提供理论参考。
Research on chemical composition and pharmacological effects and clinical application of Hedyotis hedyotidea(DC.)Merr.
Hedyotis hedyotidea(DC.)Merr.is a dried whole grass of the genus Rubiaceae.It has abundant resources and is widely distributed in Guangxi,Guangdong,Fujian,Taiwan,Guizhou,Yunnan and other places in China.Modern re-search shows that Hedyotis hedyotidea(DC.)Merr.contains terpenes,steroids,coumarins,lignans and other compounds.It has analgesic,antitumor,antibacterial,anti-inflammatory,anti-leukemia effects and other effects.At present,most of the pharmacological activity studies of Hedyotis hedyotidea(DC.)Merr.are mainly on terpenes,but there are few studies on re-lated pharmacological mechanisms.Therefore,this paper summarized the chemical composition,pharmacological effects and clinical application research of Hedyotis hedyotidea(DC.)Merr.,in order to provide a theoretical reference for the develop-ment and utilization of Hedyotis hedyotidea(DC.)Merr.in the future.

Hedyotis hedyotidea(DC.)Merr.Chemical compositionPharmacological ResearchClinical application

银胜高、陈诗曼、陆海琳、岑燕霞、程若敏

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广西中医药大学,广西 南宁 530200

牛白藤 化学成分 药理研究 临床应用

广西中医药大学广西一流学科建设开放课题(2019-2021)广西自然科学基金

2019XK0962017GXNSFAA198316

2024

药学研究
山东省药品检验所 山东省药学会

药学研究

CSTPCD
影响因子:0.653
ISSN:2095-5375
年,卷(期):2024.43(3)
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