Research progress on the ″guiding drug up″effect and dosage forms of Borneol
Borneol has a wide range of pharmacological effects in the treatment of cardiovascular and cerebrovascular diseases due to its heat-clearing and painkilling effects.At the same time,as a"drug priming",it promotes the penetration of other drugs through the blood-brain barrier by"aromatic opening the orifice and guiding drug up"and has been widely used in the design of brain-targeted drug delivery systems.Based on this,based on the pharmacological effects of Borneol,this paper focuses on the"guiding drug up"effect related mechanism of Borneol and its application in traditional compound dosage forms and modern nano-drug delivery systems.It aims to comprehensively reflect the overall progress of Borneol in the research field of"guiding drug",so as to provide a scientific reference for further exploring the medicinal value of Borneol and its modern application development research.
BorneolGuiding drug upBlood-brain barrierBrain targeted drug delivery system