Research progress in active ingredients of traditional Chinese medicine prevention and treatment of cerebral ischemia reperfusion injury
Stroke is the prime cause of death and disability in adults in China.The crucial key to treating ischemic stroke at present is to restore ischemia-reperfusion to ischemic brain tissues,and the main means is intravenous thrombolysis.However,reperfusion after ischemia may cause further neurological damage,i.e.cerebral ischemia-reperfusion injury(CIRI).Cerebral ischemia reperfusion injury(CIRI)is a serious hazard to human health.The mechanism of CIRI involves multiple cascade reactions and complex pathological mechanisms.Traditional Chinese medicine(TCM)has the characteristics of multi-component,multi-target and multi-pathway,which has great potential in prevention and treatment of CIRI.This article reviews the research progress of active ingredients of TCM,in order to provide theoretical basis for the pathological study of cerebral ischemia-reperfusion injury and provide reference for the clinical application of traditional Chinese medicine.
Cerebral ischemia reperfusion injuryActive ingredients of traditional Chinese medicineNeuroprotectionAction mechanism
万方数据
维普
