Classification and matrices of injectable in situ gels
Injectable in situ gel,as a relatively new dosage form,has a broad prospect because of its characteristics of sustained and prolonged release action,local administration at lesion site,and prevention of drug abuse and misuse.Injectable in situ gel can be passed through hypodermic needle with low applied pressure because of its low viscosity and drug reservoir is formed at the injection site due to external environmental stimuli.This review summarizes four main types of injectable in situ gel and discusses recent progress focusing on the gelling materials and drug release,aiming to provide reference for design and optimization of such preparations.
In situ gelLong-acting injectionMatricesDrug depot
万方数据
维普
