Construction and practice of full-course pharmaceutical care model for prevention of venous thromboembolism after major orthopedic surgery
Objective To establish a full-course pharmaceutical care model and working method to prevent venous thromboembolism(VTE)in patients after major orthopedic surgery,and explore its practical effect.Methods 216 patients who underwent major orthopedic surgery were collected from joint surgery in our hospital during Dec.2019-Dec.2020,and then divided into control group(108 cases)and intervention group(108 cases)according to random number table.Patients in the control group only received traditional medical services provided by doctors and nurses.Patients in the intervention group,besides the basis of the control group,clinical pharmacists participated in the clinical pathway for VTE prevention,and provided standardized pharmaceutical services,and the patients were followed up 35 days after discharge.The incidence of VTE,bleeding,medication compliance,satisfaction,medication deviation,and awareness of adverse drug events(ADE)after discharge were compared between the two groups.Results The incidence of VTE in the intervention group was 5.55％,which was lower than 19.44％in the control group(P＜0.01),and the incidence of bleeding in the intervention group was 4.60％,which was lower than 13.89％in the control group(P＜0.05).The medication compliance rate,medication guidance satisfaction and ADE awareness rate of the patients in the intervention group were significantly higher than those in the control group;the medication deviation of the patients in the intervention group was significantly lower than that in the control group.Conclusion The full-course pharmaceutical care model and work method for prevention of VTE in patients undergoing major orthopedic surgery is conducive to improving patient medication compliance and reducing the incidence of VTE,which is worth popularizing.
Clinical pharmacistsMajor orthopedic surgeryVTEPharmaceutical care
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