目的 利用CiteSpace和VOSviewer知识图谱对黄芪抗炎作用的研究现状进行可视化分析,为黄芪在抗炎方面研究提供参考。方法 以"黄芪"和"抗炎"为主题检索词,分别从中国知网数据库(CNKI)和Web of Science数据库检索中英文文献,利用CiteSpace、VOSviewer及Excel软件对中英文文献的发文量、作者、发文机构、被引频次、关键词等进行可视化分析。结果 共纳入有效文献386篇,研究黄芪抗炎功效的文献年发文量总体呈增长趋势。中英文文献发文量居首位的机构分别是天津中医药大学和中国科学院;发文量最多的作者分别是张雪梅和Dean Guo(果德安)。关键词共现、聚类显示研究热点为黄芪甲苷、黄芪多糖抗炎的药理作用以及作用机制等。结论 研究黄芪对炎症药理作用的文章逐年增加,且热点主要集中在黄芪甲苷和黄芪多糖。
Research status of Astragalus radix anti-inflammatory efficacy analysis based on CiteSpace and VOS viewer knowledge graph
Objective To use CiteSpace and VOSviewer knowledge atlas to visualize the research status of Astragalus radix anti-inflammatory effect and provide reference for the research of astragalus radix anti-inflammatory effect.Methods Using"Astragalus radix"and"anti-inflammatory"as the subject search terms,the Chinese and English literatures were retrieved from CNKI and Web of Science set databases,respectively.CiteSpace,VOSviewer,and Excel software are used to visually analyze the number of Chinese and English documents,authors,publishing institutions,citation frequency and key-words.Results A total of 386 valid literatures were included.The number of annual publications on the anti-inflammatory effect of Astragalus radix showed an overall increasing trend.Tianjin University of Traditional Chinese Medicine and Chinese Academy of Sciences ranked first in the number of Chinese and English literature publications,respectively.The authors with the most publications are Zhang Xuemei and Dean Guo,respectively.The co-occurrence and clustering of keywords showed that the research focuses on the anti-inflammatory pharmacological action and mechanism of astragaloside Ⅳ and astragalus polysaccharide.Conclusion The number of published papers about the treatment of Astragalus radix for inflammation in-creases annually,and its research hotspots mainly focus on astragaloside Ⅳ and astragalus polysaccharide.