药学研究2024,Vol.43Issue(12) :1212-1219.DOI:10.13506/j.cnki.jpr.2024.12.013

香豆素及其衍生物抗肿瘤作用研究进展

Research progress on anti-tumor effects of coumarin and its derivatives

张璐 张文 邹丽宜 尹婷 刘义
药学研究2024,Vol.43Issue(12) :1212-1219.DOI:10.13506/j.cnki.jpr.2024.12.013

香豆素及其衍生物抗肿瘤作用研究进展

Research progress on anti-tumor effects of coumarin and its derivatives

张璐 1张文 2邹丽宜 2尹婷 2刘义3
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作者信息

  • 1. 广东医科大学药学院,广东湛江 524023
  • 2. 广东医科大学药学院,广东东莞 523822
  • 3. 广东医科大学海洋与热带医学学院,广东湛江 524023
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摘要

香豆素及其衍生物是一类以苯并α-吡喃酮为核心结构的化合物,因其具有较好的抗肿瘤活性,而被研究者广泛关注.本文收集了近年来香豆素及其衍生物在抗肿瘤领域的研究文献,并对其抗肿瘤活性和作用机制进行了综述.旨在为香豆素及其衍生物的进一步研究和开发提供科学依据,推动其在肿瘤治疗中的应用.

Abstract

Coumarins and their derivatives belong to a class of compounds with the core structure of benzo-α-pyrone.They have garnered significant interest from researchers due to their potent antitumor activity.This paper presents a compre-hensive review of the recent research literature on coumarins and their derivatives in the context of antitumor activity,en-compassing their respective mechanisms of action.The objective is to establish a scientific foundation for advancing the re-search and development of coumarin and its derivatives,as well as to advocate for their utilization in cancer therapy.

关键词

香豆素/香豆素衍生物/抗肿瘤活性/作用机制

Key words

Coumarin/Coumarin derivatives/Antitumor activity/Mechanism

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出版年

2024
药学研究
山东省药品检验所 山东省药学会

药学研究

CSTPCD
影响因子:0.653
ISSN:2095-5375
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