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香豆素及其衍生物抗肿瘤作用研究进展

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香豆素及其衍生物是一类以苯并α-吡喃酮为核心结构的化合物,因其具有较好的抗肿瘤活性,而被研究者广泛关注。本文收集了近年来香豆素及其衍生物在抗肿瘤领域的研究文献,并对其抗肿瘤活性和作用机制进行了综述。旨在为香豆素及其衍生物的进一步研究和开发提供科学依据,推动其在肿瘤治疗中的应用。
Research progress on anti-tumor effects of coumarin and its derivatives
Coumarins and their derivatives belong to a class of compounds with the core structure of benzo-α-pyrone.They have garnered significant interest from researchers due to their potent antitumor activity.This paper presents a compre-hensive review of the recent research literature on coumarins and their derivatives in the context of antitumor activity,en-compassing their respective mechanisms of action.The objective is to establish a scientific foundation for advancing the re-search and development of coumarin and its derivatives,as well as to advocate for their utilization in cancer therapy.

CoumarinCoumarin derivativesAntitumor activityMechanism

张璐、张文、邹丽宜、尹婷、刘义

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广东医科大学药学院,广东湛江 524023

广东医科大学药学院,广东东莞 523822

广东医科大学海洋与热带医学学院,广东湛江 524023

香豆素 香豆素衍生物 抗肿瘤活性 作用机制

2024

药学研究
山东省药品检验所 山东省药学会

药学研究

CSTPCD
影响因子:0.653
ISSN:2095-5375
年,卷(期):2024.43(12)