Wheat is one of the three major grain crops in China,but its growth and development might be affected by multiple adverse stresses.AP2/EREBP is a superfamily of plant specific transcription factors which are widely involved in biological processeses such as growth,development and stress response.The ERF transcription class is a subfamily of the AP2/EREBP superfamily.Here,the structural characteristics and dis-tributions of ERF subfamily transcription factors in wheat were briefly introduced.And the recent research pro-gresses of the functions and mechanisms of ERF subfamily transcription factors in wheat was emphasized in re-sponse to stresses such as high salt,drought,low temperature,heavy metal and pathogen infection.Finally,the research direction and application prospect of ERF subfamily transcription factors were prospected.