Calcium is an important element affecting the growth and quality of lettuce.In order to pro-mote the growth of lettuce in plant factory with artificial light and reduce the incidence of tipburn,Italian let-tuce was chosen as material in this experiment,nutrient solution culture was adopted and four treatments were set with calcium chloride at concentrations of 0(CK,water control),0.5%(T1),1.0%(T2)and 1.5%(T3),and the effects of foliar spraying of calcium chloride on lettuce quality and tipburn were studied.The results showed that compared with CK,T2 treatment was more conducive to the growth,morphological devel-opment and improvement of each quality index of lettuce,among which,the contents of vitamin C,soluble protein and chlorophyll were the highest in all treatments.Significant improvements of lettuce tipburn could be obtained after foliar spraying of calcium chloride by delaying its onset and reducing its incidence and severity,but some quality indexes declined when the concentration was up to 1.5%.From the comprehensive evaluation results by membership function method,T2 treatment with 1.0%calcium chloride improved lettuce quality in maximum,and significantly alleviated lettuce tipburn incidence in plant factories.