首页|基于OCTA技术的单侧RVO患者健侧眼黄斑区微血管血流密度、视网膜和脉络膜厚度变化

基于OCTA技术的单侧RVO患者健侧眼黄斑区微血管血流密度、视网膜和脉络膜厚度变化

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目的 基于光学相干断层扫描血管成像(OCTA)技术,观察单侧视网膜静脉阻塞(RVO)患者健侧眼黄斑区微血管血流密度、视网膜和脉络膜厚度变化。方法 单侧RVO患者38例共76只眼,其中患眼38只记为患侧眼组,健侧眼38只记为健侧眼组。另选取同期体检健康者25例的25只正常眼作为对照组。采用美国光视公司RTVue XR 100光学相干断层扫描仪进行黄斑区微血管血流密度、视网膜和脉络膜厚度测量,包括浅层毛细血管丛(SCP)全层、上半侧、下半侧、中心凹、旁中心凹、旁中心凹上半侧、旁中心凹下半侧、旁中心凹颞侧、旁中心凹上方、旁中心凹鼻侧、旁中心凹下方的血流密度(VD),深层毛细血管丛(DCP)全层、上半侧、下半侧、中心凹、旁中心凹、旁中心凹上半侧、旁中心凹下半侧、旁中心凹颞侧、旁中心凹上方、旁中心凹鼻侧、旁中心凹下方的VD,黄斑中心凹无血管区(FAZ)面积和周长、非圆度指数(AI),黄斑中心凹为中心周围300 µm区域的视网膜(FD300)的VD,黄斑区视网膜厚度(CMT),黄斑中心凹下脉络膜厚度(SFCT)。结果 与对照组组相比,健侧眼组SCP上半侧VD、SCP旁中心凹上半侧VD、DCP旁中心凹VD、DCP旁中心凹上方VD均降低(P均<0。05);与患侧眼组相比,健侧眼组SCP全层VD、SCP上半侧VD、SCP下半侧VD、SCP旁中心凹VD、SCP旁中心凹上半侧VD、SCP旁中心凹下半侧VD、SCP旁中心凹颞侧VD、SCP旁中心凹上方VD、SCP旁中心凹鼻侧VD、SCP旁中心凹下方VD、DCP全层VD、DCP上半侧VD、DCP下半侧VD、DCP旁中心凹VD、DCP旁中心凹上半侧VD、DCP旁中心凹下半侧VD、DCP旁中心凹颞侧VD、DCP旁中心凹上方VD、DCP旁中心凹鼻侧VD、DCP旁中心凹下方VD均升高,SCP中心凹VD、DCP中心凹VD、AI、CMT均降低(P均<0。05)。结论 基于OCTA技术观察到单侧RVO患者的健侧眼黄斑区部分微血管血流密度已发生下降,但降低程度不及患侧眼,且健侧眼视网膜和脉络膜厚度变化不明显。
Changes of microvascular vascular density and thickness of retina and choroid in macular area of healthy eye in patients with unilateral RVO based on OCTA technology
Objective Based on optical coherence tomography angiography(OCTA),the changes of microvascular vascular density and retinal and choroid thickness in macular area of healthy eye in patients with unilateral retinal vein oc-clusion(ROV)were observed.Method Seventy-six eyes in 38 cases of patients with unilateral RVO,of which 38 eyes of the affected eye were recorded as the affected eye group and 38 eyes of the healthy eye were recorded as the healthy eye group.Another 25 normal eyes of 25 cases of healthy people with physical examination in the same period were selected as the control group.Macular microvascular vascular density(VD)and retinal and choroid thickness were measured by RT-Vue XR 100 optical coherence tomography,including whole image superficial capillary plexus(SCP)VD,superior-hemi SCP VD,inferior-hemi SCP VD,fovea SCP VD,parafovea SCP VD,parafovea superior-hemi SCP VD,parafovea inferior-hemi SCP VD,parafovea tempo SCP VD,parafovea superior SCP VD,parafovea nasal SCP VD,parafovea inferior SCP VD,whole image deep capillary plexus(DCP)VD,superior-hemi DCP VD,inferior-hemi DCP VD,fovea DCP VD,parafovea DCP VD,parafovea superior-hemi DCP VD,parafovea inferior-hemi DCP VD,parafovea tempo DCP VD,para-fovea superior DCP VD,parafovea nasal DCP VD,parafovea inferior DCP VD,FAZ area and perimeter,AI,FD300 VD,macular retinal thickness(CMT),and sub-foveal choroidal thickness(SFCT).Results Compared with the control group,the healthy eye group had lower superior-hemi SCP VD,parafovea superior-hemi SCP VD,parafovea DCP VD,parafovea superior-hemi DCP VD(all P<0.05).Compared with the affected eye group,the healthy eye group had higher whole image SCP VD,superior-hemi SCP VD,inferior-hemi SCP VD,parafovea SCP VD,parafovea superior-hemi SCP VD,parafovea inferior-hemi SCP VD,parafovea tempo SCP VD,parafovea superior SCP VD,parafovea nasal SCP VD,parafovea inferior SCP VD,whole image DCP VD,superior-hemi DCP VD,inferior-hemi DCP VD,parafovea DCP VD,parafovea superior-hemi DCP VD,parafovea inferior-hemi DCP VD,parafovea tempo DCP VD,parafovea superior DCP VD,parafovea nasal DCP VD,and parafovea inferior DCP VD,and lower fovea SCP VD,fovea DCP VD,AI and CMT(all P<0.05).Conclusion Based on OCTA technology,it was observed that some of the microvascular VD in the macu-lar region of the healthy eye in patients with unilateral RVO decreased,but the reduction was less than that of the affected eye,and the retinal and choroid thickness changes were not obvious in the healthy eye.

retinal vein occlusionhealthy eyeoptical coherence tomography angiographymacular areamicro-vascular vascular densityretinachoroid

万贝贝、谢英

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山西医科大学第五临床医学院,太原 030012

山西省人民医院眼科

视网膜静脉阻塞 健侧眼 光学相干断层扫描血管成像 黄斑区 微血管血流密度 视网膜 脉络膜

2024

山东医药
山东卫生报刊社

山东医药

CSTPCD
影响因子:1.225
ISSN:1002-266X
年,卷(期):2024.64(9)
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