子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素及对妊娠结局影响
Risk factors for uterine leiomyoma-associated pain syndrome in pregnancy of pregnant women with uterine leiomyoma and its influence on pregnancy outcomes
田玉翠 1王倩 2王红梅 1代荫梅3
作者信息
- 1. 首都医科大学附属北京妇产医院/北京妇幼保健院围产医学部,北京 100026
- 2. 浙江省台州市中心血站
- 3. 首都医科大学附属北京妇产医院/北京妇幼保健院妇科
- 折叠
摘要
目的 分析子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素及对妊娠结局影响.方法 395例子宫肌瘤孕妇根据是否出现妊娠期肌瘤性疼痛综合征分为病例组(74例)和对照组(321例),采用单因素分析法及多因素Logistic回归分析法分析子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素,另比较两组妊娠结局.结果 年龄是发生妊娠期肌瘤性疼痛综合征的影响因素,年龄每减小1岁,妊娠期肌瘤性疼痛综合征的风险增加0.911倍(OR=0.911,95%CI 0.852～0.973,P=0.006).病例组产后出血占22.38%、先兆早产占23.44%,对照组产后出血占35.69%、先兆早产占8.39%,两组产后出血、先兆早产发生率比较,P均<0.05.结论 子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素是年龄,肌瘤性疼痛综合征增加先兆早产的发生风险.
Abstract
Objective To evaluate the risk factors for uterine leiomyoma-associated pain syndrome in pregnancy of pregnant women with uterine fibroids and its influence on pregnancy outcomes.Methods A total of 395 pregnant women were divided into the case group of 74 cases and the control group of 321 cases according to whether uterine leiomyoma-as-sociated pain syndrome in pregnancy occurred or not.Univariate analysis and the multi-factor Logistic regression analysis was used to analyze the influencing factors for uterine leiomyoma-associated pain syndrome in pregnancy of pregnant wom-en with uterine fibroids,and additionally we compared the pregnancy outcomes of the two groups.Results Age was an influencing factor for the occurrence of uterine leiomyoma-associated pain syndrome in pregnancy and for every one-year re-duction in age,the risk of uterine leiomyoma-associated pain syndrome in pregnancy increased by 0.911 times.The rate of threatened preterm labor was higher(23.44%vs.8.39%)and the rate of postpartum hemorrhage was lower(22.38%vs.35.69%)in the case group than in the control group(all P<0.05).Conclusion Age is the influencing factor for uterine leiomyoma-associated pain syndrome in pregnancy,and the syndrome can increase the rate of threatened premature labor.
关键词
子宫肌瘤/妊娠期肌瘤相关性疼痛综合征/年龄/先兆早产Key words
uterine leiomyomas/uterine leiomyoma-associated pain syndrome in pregnancy/age/threatened pre-mature labor引用本文复制引用
基金项目
首都临床特色应用研究项目(Z111107058811031)
首都临床特色应用研究项目(Z131107002213090)
首都临床诊疗技术及示范应用研究项目(Z191100006619050)
首都医科大学附属北京妇产医院中青年学科骨干培养专项(fcyy201613)
首都医科大学附属北京妇产医院北京妇幼保健院"优青人才"计划(YQRC201905)
出版年
2024
国家科技期刊平台
NSTL
万方数据