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新冠疫情前后腹泻患儿轮状病毒感染情况对比分析

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目的 对比新冠疫情前后收治的腹泻患儿发生轮状病毒(RV)感染情况。方法 选取2017年1月—2022年12月西安医学院第一附属医院收治的腹泻患儿5 793例,将2017年1月—2020年1月定义为新冠疫情前,将2020年1月—2022年12月定义为新冠疫情后,比较新冠疫情前后腹泻患儿RV感染率。结果 新冠疫情前后腹泻患儿RV感染者分别为881例(25。29%)、587例(25。41%),新冠前后腹泻患儿发生RV感染比较差异无统计学意义(P均>0。05);新冠疫情前后不同性别腹泻患儿RV感染率比较差异无统计学意义(P均>0。05);新冠疫情前腹泻患儿RV感染率较高年龄段依次为≥1岁~<2岁、7~12个月、≥2岁~<3岁,新冠疫情后腹泻患儿RV感染较高年龄段依次为≥1岁~<2岁、≥2岁~<3岁、7~12个月,新冠前后不同年龄段腹泻患儿RV感染比较差异有统计学意义(P均<0。05);新冠疫情前腹泻患儿RV感染高发月份依次为每年12月、1月、11月,新冠疫情后腹泻患儿RV感染高发月份依次为每年1月、12月、2月,新冠前后不同月份腹泻患儿RV感染比较差异有统计学意义(P均<0。05)。结论 新冠疫情后腹泻患儿和RV感染人数虽明显减少,但RV感染仍然是儿童腹泻的主要病因;性别不是腹泻患儿发生RV感染的影响因素;腹泻患儿RV感染高发年龄段<3岁婴幼儿;除秋冬季节外春季有可能也会高发RV感染,应警惕非RV高发季节的RV筛查。
Comparative analysis of rotavirus infection in children with diarrhea before and after COVID-19 outbreak
Objective To analyze and compare the incidence of rotavirus(RV)infection in children with diarrhea before and after the COVID-19 outbreak.Methods A total of 5 793 children with diarrhea admitted to the First Affiliat-ed Hospital of Xi'an Medical University from January 2017 to December 2022 were selected.The period from January 2017 to January 2020 was defined as the time before COVID-19 epidemic,and the period from January 2020 to December 2022 was defined as the time after COVID-19 epidemic.RV infection rate of children with diarrhea before and after the COVID-19 outbreak was compared.Results There were 881(25.29%)and 587(25.41%)cases of RV infection in di-arrheal children before and after COVID-19 outbreak,respectively.There was no significant difference in RV infection in diarrheal children before and after COVID-19 outbreak(P>0.05).There was no significant difference in RV infection rate in children with diarrhea of different genders before and after COVID-19 outbreak(P>0.05).The age groups with the highest RV infection rate in children with diarrhea before COVID-19 outbreak were≥1 to<2 years old,7 to 12 months old,and≥2 to<3 years old,and the age groups with the highest RV infection rate after COVID-19 outbreak were≥1 to<2 years old,≥2 to<3 years old,and 7 to 12 months old,respectively.There were significant differences in RV infection in children with diarrhea in different ages before and after COVID-19 outbreak(all P<0.05).The months with high inci-dence of RV infection in children with diarrhea before COVID-19 outbreak were December,January and November each year,and the months with high incidence of RV infection in children with diarrhea after COVID-19 outbreak were January,December and February each year,respectively.There were statistically significant differences in RV infection in children with diarrhea in different months before and after COVID-19 outbreak(all P<0.05).Conclusions Although the number of children with diarrhea and RV infection drops significantly after COVID-19,RV infection is still the main cause of diar-rhea in children.Gender is not an influential factor in RV infection in children with diarrhea.The age of high incidence of RV infection in children with diarrhea is less than 3 years old.In addition to autumn and winter seasons,RV infection may also be high in spring,and RV screening in non-RV season should be vigilant.

diarrhearotavirusrotavirus infectiongenderageseason

陈芸、彭程、汪宇、赵凤兰、段海燕

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西安医学院第一附属医院儿科,西安 710077

腹泻 轮状病毒 轮状病毒感染 性别 年龄 季节

2024

山东医药
山东卫生报刊社

山东医药

CSTPCD
影响因子:1.225
ISSN:1002-266X
年,卷(期):2024.64(12)
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