Digital transformation is the driving force for sustainable operation and development of enterprises.Enterprises should consider how to achieve the sustainable operation and development in a scientific and reasonable way under the background of digital transformation.Under the background of digital transformation,the business process of enterprises is transformed to the integrated value chain,and the product concept is evolved to customization.The decision-making mode of enterprises is transformed to intelligence.However,during the transformation process,there are still a series of problems to be solved in the sustainable operation and management of enterprises,such as the insufficient intelligence and integration of the operation system,the convenience and integration of the business process to be improved,and the weak standard construction and application capability of the operation data.It requires enterprises to optimize and improve the above problems.It puts forwary some countermeasures.The first is to build an intensive operation system platform.The second is to carry out business process optimization and reengineering.The third is to build a data governance system for sustainable operations.This paper focuses on the research and analysis of enterprise sustainable operation management strategies under the background of digital transformation,aiming to provide certain suggestions for similar work and promote the healthy and sustainable development of enterprises.