Preparation and in Vitro Evaluation of Acetaminophen Ointment
To prepare acetaminophen ointment and evaluate it in vitro,so as to understand the effect of ointment matrix type on drug release and provide basis for the preparation of acetaminophen ointment.Acetaminophen ointment was prepared with 5 different types of ointment matrix,and the drug diffusion rate in each type of ointment matrix was determined by agar diffusion method.The release rate of acetaminophen in gel matrix was the fastest.Acetaminophen should be made into gel ointment.
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