Technological Transformation of Anhydrous Tetramethylpyrazine
The modification problem of anhydrous tetramethylpyrazine process was studied.Through the analysis and evaluation of existing processes,the process of synthesizing 2,3,5,6-tetramethylpyrazine using acetoin was studied.Different reaction temperatures,times,catalyst feeding methods,and the selection of dehydrating agents were investigated.The results showed that the initial temperature of the reaction between acetoin and ammonium acetate was 60℃.When the reaction time is controlled at 2 hours,the total yield of 2,3,5,6-tetramethylpyrazine can reach over 79%,and anhydrous ethanol is used as the solvent as the dehydrating agent.The melting point of anhydrous tetramethylpyrazine can reach 85℃.This study demonstrated through experimental verification that the process performance of anhydrous tetramethylpyrazine was significantly improved after modification.
NETL
NSTL
万方数据
