Analysis of the Structure and Properties of 2-MDCK
2-(methylamino)-2-(o-tolyl)cyclohexan-1-one),2-MDCK,is one analogue of ketamine,therefore,it still has the similar affections as ketamine,including neural inhibition,excitation,analgesia,psychoactive,etc.In this report,the spectrums of 2-MDCK were characterized by Gas chromatography-mass spectrometry(GC-MS),Liquid chromatography-mass spectrometry(LC-MS)and Nuclear magnetic resonance spectroscopy(NMR),Fourier transform infrared spectroscopy(FT-IR)and Ultraviolet visible absorption spectroscopy(UV-Vis),and then the chemical structure of 2-MDCK was defined through combining following two methods.To simulate the possible splitting pathways of 2-MDCK by deducing the structure of the fragment ions,and to analyze the 1H/13C/DEPT/HMBC NMR spectrums.This work proposes a collaborative characterization analysis approach that combines multiple analytical methods,which can provide reference for identifying such substances or new unknown compounds.
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