透明质酸修饰的氮化硼在黑色素瘤中的靶向性能研究
Study on Targeting Performance of the Hyaluronic acid Modified Boron Nitride in Melanoma
文利平 1解晓伟1
作者信息
- 1. 广东工业大学轻工化工学院,广东 广州 510006
- 折叠
摘要
本文使用对黑色素瘤有靶向性的透明质酸,修饰氮化硼纳米材料,研究了靶向分子的表面修饰对于氮化硼靶向性能的影响.紫外和红外表征检测了修饰前后的特征峰变化,表明了靶向分子对氮化硼的成功修饰.以B16F10黑色素瘤细胞和L929正常细胞为研究对象,通过T/N测试考察修饰前后氮化硼的靶向性能.
Abstract
In this paper,hyaluronic acid,which targets melanoma,was used to modify boron nitride nanomaterials and the effect of surface modification of targeted molecules on the targeting performance of boron nitride was investigated.UV-vis and infrared characterization methods were used to test the changes in characteristic peaks before and after modification,which confirmed the successful loading of targeted molecules on boron nitride.B16F10 melanoma cells and L929 normal cells were used to explore the targeting performance of boron nitride before and after modification through T/N(tumor to normal)testing.
关键词
氮化硼/透明质酸/表面修饰/黑色素瘤/靶向性Key words
boron nitride/hyaluronic acid/surface modification/melanoma/targeting performance引用本文复制引用
出版年
2024
NETL
NSTL
万方数据