Study on Targeting Performance of the Hyaluronic acid Modified Boron Nitride in Melanoma
In this paper,hyaluronic acid,which targets melanoma,was used to modify boron nitride nanomaterials and the effect of surface modification of targeted molecules on the targeting performance of boron nitride was investigated.UV-vis and infrared characterization methods were used to test the changes in characteristic peaks before and after modification,which confirmed the successful loading of targeted molecules on boron nitride.B16F10 melanoma cells and L929 normal cells were used to explore the targeting performance of boron nitride before and after modification through T/N(tumor to normal)testing.