Research progress on pathogenesis of polycystic ovary syndrome and traditional Chinese medicine intervention based on LncRNA
Polycystic ovary syndrome(PCOS)is a clinically common metabolic syndrome that affects the men-tal health and quality of life of many women.With the continuous exploration and development of molecular biology,Long non-coding RNA(LncRNA)has been shown to play an important role in the occurrence and development of P-COS.Traditional Chinese medicine(TCM)has the characteristics of multi-target,multi-pathway,small side effects and high cure rate,and has significant clinical effect in the prevention and treatment of PCOS,but its molecular mech-anism has not been clarified.The article reviews the pathogenisis of various LncRNA involved in PCOS and its com-plications,and summarizes the current research progress of TCM monomer,compound and special therapy to im-prove PCOS and its complications by regulating LncRNA.so as to provide theoretical basis for clarifying the patho-genesis of PCOS.It provides a new target for improving PCOS by TCM and a new idea for clinical prevention and treatment of disease.
Polycystic ovary syndromeLong non-coding RNAPathogenesisTraditional Chinese medicineInsulin resistanceHyperandrogenemiaObesity
万方数据
维普
