Polycystic ovary syndrome(PCOS)is a clinically common metabolic syndrome that affects the men-tal health and quality of life of many women.With the continuous exploration and development of molecular biology,Long non-coding RNA(LncRNA)has been shown to play an important role in the occurrence and development of P-COS.Traditional Chinese medicine(TCM)has the characteristics of multi-target,multi-pathway,small side effects and high cure rate,and has significant clinical effect in the prevention and treatment of PCOS,but its molecular mech-anism has not been clarified.The article reviews the pathogenisis of various LncRNA involved in PCOS and its com-plications,and summarizes the current research progress of TCM monomer,compound and special therapy to im-prove PCOS and its complications by regulating LncRNA.so as to provide theoretical basis for clarifying the patho-genesis of PCOS.It provides a new target for improving PCOS by TCM and a new idea for clinical prevention and treatment of disease.
关键词
多囊卵巢综合征/长链非编码RNA/发病机制/中医药/胰岛素抵抗/高雄激素血症/肥胖
Key words
Polycystic ovary syndrome/Long non-coding RNA/Pathogenesis/Traditional Chinese medicine/Insulin resistance/Hyperandrogenemia/Obesity
维普
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