Taking a 2×1 050 MW ultra-supercritical unit of a power plant as the research object,the quality control tool was used to improve the distribution uniformity of NOx in the power plant.The problem existing in the denitration spray ammonia grid spray ammonia system was introduced,the improvement objective was put forward,then the optimization countermeasure by using the quality control tool was proposed,and the result was examined.Using quality control tool can improve the distribution uniformity of NO,in the power plant in a scientific and efficient way,and achieve the purpose of improving quality and efficiency.