Baduanjin improves sleep quality in patients with type 2 diabetes possibly via regulating Bmal1 gene
The incidence of diabetes mellitus is increasing,and the sleep quality of patients with diabetes mellitus is often affected.Baduanjin may act on biological rhythm of the body,skeletal muscle glucose metabolism,skeletal muscle fibers and suprachiasmatic nucleus(SCN)by regulating the expression of Bmal1 gene,thus regulating the blood glucose level and circadian rhythm of patients with type 2 diabetes mellitus(T2DM)and improving their physiological functions.This article reviews the regulatory effect and mechanism of Baduanjin on Bmal1 gene expression in diabetes patients,and discusses the possibility of Baduanjin to improve the sleep quality of T2DM patients by regulating Bmal1 gene expression.This review can provide a new field for the clinical application of traditional Chinese Qigong Baduanjin,and provide a new scientific basis for exercise therapy of diabetes.
BaduanjinBmal1diabetes mellitussleep quality
董子萱、马占科
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宁夏师范大学体育学院,固原 756099
八段锦 Bmal1 糖尿病 睡眠质量
Scientific Research Project of Higher Education Department of Ningxia Hui Autonomous Region,China