Research progress on eosinophil heterogeneity in asthma
Asthma is a heterogeneous disease characterized by chronic airway inflammation.More than half of asthma cases are induced by allergens.Eosinophils accumulate in large numbers in the airways,and their number is closely related to the severity of asthma.In recent years,extensive research has been conducted on the pathogenesis of eosinophils in asthma and the targeted thera-peutic drugs for them.This article mainly reviews the research progress on the important role of eosinophil heterogeneity in the occur-rence and development of asthma,and provides ideas for the personalized and precise treatment of asthma in the future.
asthmaairway inflammationeosinophilheterogeneity
陈严、应颂敏、张超
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浙江大学呼吸疾病研究所,杭州 310030
浙江大学医学院附属第二医院呼吸与危重症医学科,杭州 310009
浙江大学国际健康医学研究院,义乌 322000
哮喘 气道炎症 嗜酸性粒细胞 异质性
National Natural Science Foundation of ChinaNational Natural Science Foundation of China
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