Research progress on anti-aging effects of β-nicotinamide mononucleotide(NMN)
β-Nicotinamide mononucleotide(NMN),as the precursor of nicotinamide adenine dinucleotide(NAD),plays an important role in enhancing NAD levels.Intake of NMN can alter the composition and vitality of gut microbiota,restore mitochondrial func-tion,inhibit inflammatory pathways,improve metabolism,counteract oxidative stress,and alleviate inflammation.NMN significantly improves recovery from aging-related diseases,such as diminished heart function,reduced fertility,memory decline,and diabetes.NMN demonstrates both efficacy and safety in anti-aging.The use of NMN in China has gradually gained acceptance,highlighting the importance of exploring the mechanism of NMN in anti-aging effects and improving the biosynthesis of NMN.In addition,NMN in combination with stem cells hold promise in the treatment of aging-related degenerative diseases and promote overall human and animal health.