人工肌腱/韧带生物材料研究进展
Advances in biomaterials of artificial tendon/ligament
杨冬逸 1李刚2
作者信息
- 1. 苏州大学纺织与服装工程学院,江苏苏州 215000
- 2. 苏州大学纺织与服装工程学院,江苏苏州 215000;苏州大学现代丝绸国家工程实验室,江苏苏州 215123;南通纺织丝绸技术研究院,江苏南通 226300
- 折叠
摘要
随着人们预期寿命的延长和高强度运动的普及,肌腱/韧带(TL)损伤的频率也随之增加.由于其组织的特异性,受损肌腱和韧带的快速恢复对治疗极具挑战性.基于不同生物材料、制备技术、生物活性分子和细胞等在治疗修复TL损伤方面的最新进展,介绍了TL损伤与治疗的现状,回顾了天然生物聚合物和合成生物聚合物材料在TL组织修复中的应用,讨论了当前TL组织支架的制备技术和再生策略,以期为TL组织修复生物材料的开发提供参考.
Abstract
With increasing life expectancy and the popularity of high-intensity exercise,the frequency of tendon/ligament(TL)injuries has increased,and rapid recovery of damaged tendons and ligaments is challenging to treat due to their tissue specificity.Based on the latest progress of different biomaterials,preparation techniques,bioactive molecules and cells in the treatment and repair of TL damage,the status quo of TL damage and treatment is introduced,the application of natural biopolymer and synthetic biopolymer materials in TL tissue repair is reviewed,and the current preparation techniques and regeneration strategies of TL tissue scaffolds are discussed,in order to provide a new idea for the development of TL tissue repair biomaterials.
关键词
TL损伤/生物材料/聚合物/组织支架/制备技术/再生策略Key words
TL injury/biomaterial/polymer/tissue scaffold/preparation technology/regeneration strategy引用本文复制引用
基金项目
国家重点研发计划(2021YFE0111100)
科技部对发展中国家常规性科技援助项目(KY202201002)
江苏省科技计划专项(BZ2022017)
江苏省先进纺织工程技术中心创新项目(XJFZ/2021/7)
中国纺织工业联合会"纺织之光"应用基础研究计划项目(J202002)
出版年
2024
NETL
NSTL
万方数据