Degradable nanofibers based drug delivery system and its biomedical applications
Degradable polymers can be absorbed and self-degradated by the human body,reducing secondary damage and bacterial infection.Electrospinning is a simple method to obtain nanofibers.Nanofibers with different structures can be obtained by changing spinning technology and controlling process parameters.Electrospun nanofibers usually have high porosity and high specific surface area,which can stably load drugs and achieve controlled release of drugs,which have a wide range of applications in the biomedical fields.Based on the current research status at home and abroad,the commonly used electrospinning degradable raw materials and their characteristics are introduced,different electrospinning drug loading methods are discussed,and the application and research progress of nanofiber-based drug loading systems in biomedicine are summarized.Finally,the future direction of the research is prospected.
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