Preparation of PVA/CS and PEO/SA bilayer nanofiber films and their properties
To investigate the application of highly biocompatible raw materials in medical dressings,PVA/CS and PEO/SA bilayer nanofiber membranes are prepared using electrospinning method,and subjected to water repellent treatment and cross-linking treatment.The mechanical and antibacterial properties of the bilayer nanofiber membranes are analyzed.Levofloxacin hydrochloride is added and its sustained-release mechanism is studied.The results show that the spinning solution with PVA mass fraction of 14%and CS mass fraction of 3%has good spinnability at spinning voltage of 26 kV and receiving distance of 20 cm,while the spinning solution with PEO mass fraction of 10%and SA mass fraction of 2%has good spinnability at spinning voltage of 27 kV and receiving distance of 20 cm.The prepared bilayer nanofiber membranes of PVA/CS blend and PEO/SA blend have hydrophilicity and potential antibacterial properties,which have unique advantages in the field of biomedicine.