To investigate the application of highly biocompatible raw materials in medical dressings,PVA/CS and PEO/SA bilayer nanofiber membranes are prepared using electrospinning method,and subjected to water repellent treatment and cross-linking treatment.The mechanical and antibacterial properties of the bilayer nanofiber membranes are analyzed.Levofloxacin hydrochloride is added and its sustained-release mechanism is studied.The results show that the spinning solution with PVA mass fraction of 14％and CS mass fraction of 3％has good spinnability at spinning voltage of 26 kV and receiving distance of 20 cm,while the spinning solution with PEO mass fraction of 10％and SA mass fraction of 2％has good spinnability at spinning voltage of 27 kV and receiving distance of 20 cm.The prepared bilayer nanofiber membranes of PVA/CS blend and PEO/SA blend have hydrophilicity and potential antibacterial properties,which have unique advantages in the field of biomedicine.
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