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Time-Resolved Imaging in Short-Wave Infrared Region

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Compared with the conventional first near-infrared(NIR-I,700-900 nm)window,the short-wave infrared region(SWIR,900-1700nm)possesses the merits of the increasing tissue penetration depths and the suppression of scattering background,leading to great potential for in vivo imaging.Based on the limitations of the common spectral domain,and the superiority of the time-dimension,time-resolved imaging eliminates the auto-fluorescence in the biological tissue,thus supporting higher signal-to-noise ratio and sensitivities.The imaging technique is not affected by the difference in tissue composition or thickness and has the practical value of quan-titative in vivo detection.Almost all the relevant time-resolved imaging was carried out around lanthanide-doped upconversion nanomaterials,owing to the advantages of ultralong luminescence lifetime,excellent photostability,controllable morphology,easy surface modification and various strategies of regulating lifetime.Therefore,this review presents the research progress of SWIR time-resolved imaging technology based on nanomaterials doped with lanthanide ions as luminescence centers in recent years.

time-resolved imagingshort-wave infraredfluorescence probelanthanide ions

徐杨、李万万

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School of Materials Science and Engineering,Shanghai Jiao Tong University,Shanghai 200240,China

国家自然科学基金国家重点研发计划Translational Medicine Research Fund of National Facility for Translational Medicine(Shanghai)

819717042017YFA0205304TMSK-2021-117

2024

上海交通大学学报(英文版)
上海交通大学

上海交通大学学报(英文版)

影响因子:0.151
ISSN:1007-1172
年,卷(期):2024.29(1)
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