4例抗核抗体人喉癌上皮细胞核型AC-29患儿的病例分析

Four case reports of a newly defined HEp-2 ANA karyotype AC-29 by indirect immunofluorescence assay

李晨丽 ¹潘伟¹

扫码查看

作者信息

1. 南京医科大学附属儿童医院检验科,南京 210008
折叠

摘要

为探讨人喉癌上皮细胞DNA拓扑异构酶Ⅰ型(AC-29)病例的临床特点,回顾性分析南京医科大学附属儿童医院4例AC-29核型患儿的临床特征.结果显示,2020年1月至2021年12月期间南京医科大学附属儿童医院共检测自身抗体阳性血清样本14 213例,其中4例抗核抗体(间接免疫荧光法)核型为AC-29.AC-29是近年新定义的一类核型,正确识别对疾病早期的诊断有一定提示意义.

Abstract

To explore the clinical characteristics of DNA topoisomerase type Ⅰ(AC-29)in human laryngeal carcinoma cell line 2(HEp-2)cells,four cases of AC-29 from Children's Hospital of Nanjing Medical University were retrospectively reported.From January 2020 to December 2021,a total of 14 213 serum samples with auto-antibodies had been tested in this Hospital.Among them,four had the anti-nuclear antibody(ANA)karyotype shaped AC-29 tested by indirect immunofluorescence assay.AC-29 is a newly defined karyotype in recent years.Correct identification of AC-29 has potential significance for early diagnosis of disease.

关键词

抗核抗体/HEp-2细胞/DNA拓扑异构酶Ⅰ型

Key words

anti-nuclear antibody/human laryngeal carcinoma cell line 2 cell/deoxyribonucleic acid topoisomerase type Ⅰ

引用本文复制引用

基金项目

南京医科大学科技基金(NMUB20210078)

出版年

2024

现代免疫学

上海市免疫学研究所,上海市免疫学会

现代免疫学

CSTPCD

影响因子：0.4

ISSN：1001-2478

参考文献量5

段落导航