首页|4例抗核抗体人喉癌上皮细胞核型AC-29患儿的病例分析

4例抗核抗体人喉癌上皮细胞核型AC-29患儿的病例分析

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为探讨人喉癌上皮细胞DNA拓扑异构酶Ⅰ型(AC-29)病例的临床特点,回顾性分析南京医科大学附属儿童医院4例AC-29核型患儿的临床特征.结果显示,2020年1月至2021年12月期间南京医科大学附属儿童医院共检测自身抗体阳性血清样本14 213例,其中4例抗核抗体(间接免疫荧光法)核型为AC-29.AC-29是近年新定义的一类核型,正确识别对疾病早期的诊断有一定提示意义.
Four case reports of a newly defined HEp-2 ANA karyotype AC-29 by indirect immunofluorescence assay
To explore the clinical characteristics of DNA topoisomerase type Ⅰ(AC-29)in human laryngeal carcinoma cell line 2(HEp-2)cells,four cases of AC-29 from Children's Hospital of Nanjing Medical University were retrospectively reported.From January 2020 to December 2021,a total of 14 213 serum samples with auto-antibodies had been tested in this Hospital.Among them,four had the anti-nuclear antibody(ANA)karyotype shaped AC-29 tested by indirect immunofluorescence assay.AC-29 is a newly defined karyotype in recent years.Correct identification of AC-29 has potential significance for early diagnosis of disease.

anti-nuclear antibodyhuman laryngeal carcinoma cell line 2 celldeoxyribonucleic acid topoisomerase type Ⅰ

李晨丽、潘伟

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南京医科大学附属儿童医院检验科,南京 210008

抗核抗体 HEp-2细胞 DNA拓扑异构酶Ⅰ型

南京医科大学科技基金

NMUB20210078

2024

现代免疫学
上海市免疫学研究所,上海市免疫学会

现代免疫学

CSTPCD
影响因子:0.4
ISSN:1001-2478
年,卷(期):2024.44(1)
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