Research progress of the functions of virus infection-induced mitochon-drial damage in T cell senescence
Aging is an inevitable stage in the metabolic process of human body which also affects the immune system,among which the changes of T cells are the most obvious.Mitochondrial dysfunction is one of the important reasons for cellular senes-cence.Recent studies have shown that viral infection can alter the metabolism of host cells by inducing mitochondrial damage which causes immunosenescence.This review aims to summarize the research progress on the role of virus infection-induced mitochondrial damage in T cell senescence including mitochondrial function,the effect of virus infection on mitochondrial damage,and the relationship between mitochondrial damage and T cell senescence.
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