Research progress of sex hormones in Sj?gren's syndrome
Sex hormones are steroid hormones secreted by gonads and adrenal glands or converted from other substances.Sjögren's syndrome(SS)is a chronic progressive systemic autoimmune disease mediated by lymphocytes,mainly affecting exocrine glands.Due to the complex etiology,its pathogenesis has not been fully elucidated.The fact that the incidence of SS is higher in women than in men suggests a relationship between sex hormones and the development of SS.This review discusses the mechanism and influence of estrogen,androgen,and prolactin on SS to provide reference to understand the pathogenesis of SS and explore the therapeutic strategies.
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