Research progress of obesity associated T cell metabolic disorder and related diseases
Obesity increases the risk of infectious and neoplastic diseases.Studies have found that obesity may cause T cell metabolism disorders by affecting T cell lipid and carbohydrate metabolisms,promoting the release of inflammatory factors,and T cell aging,thereby increasing the mortality upon infection.Obesity is also an important risk factor associated with the prevalence of diseases.Obesity is associated with poor prognosis of neoplastic diseases,which is the combined effect of multiple factors affecting immune metabolism and inflammation.This review summarizes the research progress on T lymphocyte metabolism disorders caused by obesity and the role of T lymphocyte metabolism disorders in infectious and neoplastic diseases and treatment prospects.
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