Progress in boron-based compounds for tumor diagnosis and treatment
After the World Health Organization(WHO)declared that boron(B)is a"possible essential element"for human beings,boron-based composites have become a new research hotspot in the biomedical field.The results show that boron and its derivatives exhibit anticancer properties in many directions,including radiotherapy,combined therapy,regulation of cell signal expression,and biochemical processes.In addition,five boron-containing drugs approved by Food and Drug Administration(FDA)in the United States have greatly affected the application of boron and its derivatives in medicinal chemistry,chemical biology,drug delivery,biomaterial exploration,pharmacological improvement,and nutrition.In this paper,various types of boron-based materials and their potential applications in pharmacy and tumor treatment are reviewed in order to contribute to the further development and innovation of boron-containing compounds.