Research progress of albendazole medicinal preparations
Albendazole(ABZ)is a benzimidazole derivative which was mainly used as an antiparasitic drug to treat nematode diseases such as hookworm,roundworm,and trichuris,as well as cysticercosis and echinococcosis.Due to its low solubility and widespread distribution in vivo,ABZ is difficult to be absorbed in vivo and has low bioavailability.In recent years,in order to improve the bioavailability and efficacy of ABZ,a series of new ABZ formulations have been developed.This article reviews the research progress of ABZ medicinal preparations in the past two decades.
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