Advantages of COVID-19 vaccine in the T cell immune response
[Objective]To illustrate the mechanism of COVID-19 vaccine in the T cell immune response.[Methods]Based on the characteristics of T cell and B cell immune response,we matched the data of incubation periods across the SARS-CoV-2 prototype strain,Delta variants,and Omicron variants and effectiveness of mRNA and inactivated COVID-19 vaccines for analysis.[Results]The effectiveness of mRNA COVID-19 vaccine against infection and onset was consistent with incubation period principally being≥5 days.In contrast,the effectiveness of inactivated COVID-19 vaccine was consistent with incubation period principally being≥8 days.[Conclusion]It may be interpreted by faster T cell immune response stimulated by mRNA vaccine,compared to B cell immune response by inactivated vaccine.
SARS-CoV-2mRNA vaccineinactivated vaccineT cell and B cell immune response