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不同人机共存消毒方法的空气消毒效果

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[目的]比较不同人机共存消毒方法对医疗机构空气传播疾病高风险场所的空气消毒效果,为医疗机构空气传播疾病防控提供参考.[方法]在某三级甲等医院发热门诊、感染病科和口腔科开展现场试验,各场所均采用原有空气消毒方法(等离子体空气消毒器/循环风紫外线空气消毒器/负压)、222 nm紫外线上层空间消毒、原有空气消毒方法联合222 nm紫外线上层空间消毒进行空气消毒,对照组不采取特定空气消毒方法.通过六级筛孔撞击式微生物采样法或沉降法进行空气采样,每日空气采样时间段为8:00-16:00,每小时采样1次,共采样9次.比较各种消毒方法的空气细菌总数和杀菌率.[结果]222 nm组发热门诊输液室、感染病科病房和护士站的空气细菌总数低于对照组(P=0.005,P<0.001,P<0.001).222 nm组发热门诊输液室和口腔科诊室的空气细菌总数低于等离子体组(P=0.022,P=0.014).等离子体联合222 nm组核酸采样室的空气细菌总数低于等离子体组(P=0.019).222 nm组发热门诊CT室的空气细菌总数低于循环风紫外线组(P=0.002).循环风紫外线联合222 nm组发热门诊CT室的空气细菌总数低于循环风紫外线组和对照组(P=0.008,P<0.001).222 nm紫外线上层空间空气杀菌率为48.04%～73.74%.等离子空气消毒器/循环风紫外线空气消毒器联合222 nm紫外线上层空间空气杀菌率为6.86%～73.77%.[结论]在空气传播风险较高的门诊和病房环境中,222 nm紫外线上层空间消毒可有效降低空气菌落数,改善空气卫生质量.
Air disinfection effect of different human-machine coexistence disinfection methods
[Objective]To compare the air disinfection effects of different human-machine coexistence disinfection methods in the high-risk areas of airborne diseases in medical and healthcare institutions,and to provide a reference for the prevention and control of airborne diseases in medical and healthcare institutions.[Methods]Field trials were conducted in the fever clinic,the infection disease department,and dental clinics of a tertiary hospital in Shanghai,respectively.The existing air disinfection methods(plasma air disinfection machine,circulating air ultraviolet disinfection machine or negative pressure ventilation system),upper-room 222 nm ultraviolet germicidal system,and the combination of the existing air disinfection methods and upper-room 222 nm ultraviolet germicidal system were all used in each location in the experiment group.The control group did not adopt specific air disinfection methods.Air sampling was conducted by the six-level sieve hole microbial sampler or the flat slab exposure method.The daily air sampling time was from 8:00 a.m.to 16:00 p.m.,with one sample per hour,and a total of 9 samples were taken.The disinfection effects were compared by calculating the total number of airborne bacteria colonies and the sterilization rate for each disinfection method.[Results]The total numbers of airborne bacteria colonies in the fever outpatient infusion room,the ward and nurse station of infection disease department of 222 nm group were lower than that in the control group(P=0.005,P<0.001,P<0.001).The total numbers of airborne bacteria colonies in the fever outpatient infusion room and the dental examination room of 222 nm group were lower than that in the control group or plasma air disinfection machine group(P=0.022,P=0.014).The total numbers of airborne bacteria colonies in the nucleic acid sampling room of plasma air disinfection machine group combined with 222 nm group were lower than that in plasma air disinfection machine group(P=0.019).The total numbers of airborne bacteria colonies in the CT examination room of fever clinic of the 222 nm group were lower than that in the circulating air ultraviolet disinfection machine group(P=0.002).The total numbers of airborne bacteria colonies in the CT examination room of 222 nm group combined with circulating air ultraviolet disinfection machine were lower than that of circulating air ultraviolet disinfection machine group and the control group(P=0.008,P<0.001).The air sterilization rate of upper-room 222 nm ultraviolet germicidal system ranged from 48.04%to 73.74%.The air sterilization rate of plasma air/circulating air ultraviolet disinfection machine combined with the upper-room 222 nm ultraviolet germicidal system ranged from 6.86%to 73.77%.[Conclusion]Upper-room 222 nm ultraviolet germicidal system could effectively reduce airborne colonies in the air and improve air hygiene quality in both clinic and ward environments with high airborne transmission risks.

air disinfectionhuman-machine coexistencemedical and healthcare institution222 nm ultravioletupper-room ultraviolet germicidal system

韩梦鸽、崔一忻、孙伟、胡必杰、高晓东

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复旦大学附属中山医院感染管理科,上海 200032

复旦大学附属中山医院感染病科,上海 200032

空气消毒 人机共存 医疗机构 222nm紫外线 上层空间紫外线消毒

上海市加强公共卫生体系建设三年行动计划(2023-2025年)重点学科上海申康医院发展中心市级医院临床科技创新项目上海市院感防控和实验室生物安全能力建设项目

GWVI-11.1-04SHDC22021315GWVI-13

2024

10.19428/j.cnki.sjpm.2024.24467

上海预防医学
上海市预防医学会

上海预防医学

CSTPCD
影响因子：0.615
ISSN：1004-9231
年,卷(期)：2024.36(9)