Research on herbal efficacy and modern pharmacology of fresh Rehmannia
Based on the efficacy of fresh Rehmannia recorded in traditional Chinese herbal medicine,the modern clinical application of fresh Rehmannia and the research progress of its pharmacodynamic substances were investigated by searching CNKI,Wanfang database and VIP database.The results showed that fresh Rehmannia can promote blood and produce new blood,disperse blood stasis and relieve pain,and nourish Yin and rejuvenating Jin besides the effects of clearing heat and rejuvenating Jin,cooling blood and stopping bleeding recorded in the 2020 edition of Chinese Pharmacopoeia.Fresh Rehmannia and its related compounds are widely used in the treatment of trauma bleeding,congestion,dysmenorrhea,intra-partum injury,typhoid palpitation,TCM delirium(maniac,lily disease),thirst quenching,heat poison sores,fever Yin injury,plague disease and so on.Modern pharmacological studies show that the main active ingredients of fresh Rehmannia are catalpol,ergosterin and so on,which have antioxidant,anti-inflammatory,neuroprotective and insulin resistance improvement effects.Fresh Rehmannia and its related compounds have a good clinical effect on chronic hepatitis,oral mucosal adverse reactions after radiotherapy for nasopharyngeal cancer,stele,chalazion,depression,insomnia,anxiety and so on.