Application effect of different proportions of plasma and red blood cell infusion in the treatment of postpartum hemorrhage
Objective:To observe the application effect of different proportions of plasma and red blood cell(RBC)infusion in the treatment of postpartum hemorrhage.Methods:Ninety patients with postpartum hemorrhage admitted to the hospital from April 2021 to July 2022 were selected and divided into group A,group B and group C with 30 cases in each group by random number table method.Group A received 0.5∶1 infusion of plasma to RBC,group B received 1∶1 infusion of plasma to RBC,and group C received 1.5∶1 infusion of plasma to RBC.Blood routine indexes[hemoglobin(Hb),platelet(PLT)],coagulation function indexes[fibrinogen(FBG),prothrombin time(PT),activated partial thrombin time(APTT)]and the occurrence of adverse reactions were compared among the three groups.Results:The levels of Hb and PLT in the three groups were higher at 24h than those before transfusion,and the levels of Hb and PLT in group B were higher than those in group A and group C,and the difference was statistically significant(P<0.05).After 24h of transfusion,the FBG level of the three groups was higher than that before transfusion,while PT and APTT were lower than those before transfusion,and the FBG level of group B was higher than that in group A and C,while PT and APTT were lower than those in group A and C,and the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions among the three groups(P>0.05).Conclusion:The 1∶1 ratio of plasma to RBC infusion is better for postpartum hemorrhage patients,which can improve coagulation function and has good safety.
postpartum hemorrhagetransfusion therapyblood clotting function
万方数据
维普
