Applications of synthetic biology in the pharmaceutical field
In the past two decades,synthetic biology has made breakthroughs in the construction of biocircuits,the standardization of biological elements and the development of various genomic/metabolic engineering tools and approaches.Its rapid development is changing the industrial layout of biotechnology industry.At present,synthetic biotechnology has been widely used in many fields such as natural product synthesis,medicine,energy and industry.Pharmaceutical demands have also driven its development,including the application of in vitro catalytic technology in the green manufacturing of chiral pharmaceutical chemicals and the integration of heterologous pathways into designer cells to efficiently produce medicines and so on.Synthetic biology,with its more economical and environmentally friendly features,will subvert some traditional pharmaceutical manufacturing methods.This article reviews the applications of synthetic biology in the green manufacturing of chiral pharmaceutical chemicals and the biological manufacturing of natural plant products.
NETL
NSTL
万方数据
维普
