Effects of remimazolam combined with rocuronium bromide on HR,SpO2,MAP and muscle relaxation in rapid sequential induction of emergency patients
Objective:To study the effects of remimazolam combined with rocuronium bromide on heart rate(HR),pulse oxygen saturation(SpO2),mean artery pressure(MAP)and muscle relaxation in rapid sequential induction for emergency patients.Methods:Eighty patients undergoing emergency surgery were randomly divided into a control group and a study group with 40 cases each.During anesthesia induction,the control group was given midazolam and rocuronium bromide,while the study group was given remimazolam and rocuronium bromide.The anesthetic effect,respiratory and circulatory indexes and muscle relaxation effect in the two groups were monitored and recorded.Results:The success rate of sedation in both groups was 100%.Compared with the control group,the times for consciousness disappearance,anesthesia induction,eyelash reflex disappearance,onset,postanesthesia care unit retention and awakening were all shorter,MAP,SpO2,MAP and respiratory frequency fluctuated slightly,the incidence of hypotension was low,and the clinical action time and recovery index of muscle relaxants were longer in the study group(all P<0.05).Conclusion:The combination of remimazolam and rocuronium bromide for rapid sequential induction has good hemodynamic stability and can extend the time of muscle relaxation.
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