Effect of remimazolam versus propofol on postoperative cognitive function and quality of recovery in colonoscopy patients:a comparative clinical study
Objective:To investigate the clinical effects of remimazolam and propofol on postoperative cognitive function and recovery quality in colonoscopy patients.Methods:One hundred and fifty patients undergoing colonoscopy were randomly divided into group P and group R,with 75 cases each.Group P was anesthetized with propofol,while group R was anesthetized with remimazolam benzenesulfonate.The time for anesthesia and awakening,bispectral index(BIS)value,cognitive function[Montreal cognitive assessment(MoCA)scale]and adverse reactions were compared between the two groups.Results:The onset of anesthesia and the time from the end of the examination to awakening were shorter,the BIS values at 5 min of medication,at the time of colonoscopy placement,at 5 min of colonoscopy placement,and at the end of the procedure,as well as the MoCA scale scores at the time of awakening were higher,and the incidence of adverse reactions was lower in the group R than the group P(P<0.05).Conclusion:Compared with propofol,remimazolam is more effective in anesthesia for patients with colonoscopy and has less effect on patients'BIS value and cognitive function,which is more conducive to patients'postoperative recovery and safer.
NETL
NSTL
万方数据
维普
