血栓通联合前列地尔治疗55例下肢动脉硬化闭塞症患者的疗效观察
Effect of Xueshuantong combined with alprostadil in the treatment of 55 patients with lower limb atherosclerotic occlusive disease
娄浩然 1叶郁青1
作者信息
- 1. 郑州大学附属郑州中心医院血管外科 郑州 450001
- 折叠
摘要
目的:探讨血栓通联合前列地尔治疗下肢动脉硬化闭塞症的疗效.方法:将 110例下肢动脉硬化闭塞症患者按入院时间分为对照组和观察组各 55 例,对照组行前列地尔治疗,观察组在此基础上给予血栓通治疗,比对 2 组治疗前后踝肱指数(ABI)和趾肱指数(TBI)指数、血流动力学指标、不良反应发生率,以及治疗有效率.结果:治疗后,观察组治疗有效率、ABI和TBI指数均高于对照组;血流动力学指标、不良反应发生率均低于对照组(均P＜0.05).结论:采用血栓通联合前列地尔治疗下肢动脉硬化闭塞症,疗效确切,可有效改善患者血流动力学指标,提高患者生活质量.
Abstract
Objective:To explore the therapeutic effect of Xueshuantong combined with alprostadil in the treatment of lower limb atherosclerotic occlusive disease.Methods:One hundred and ten patients with lower limb atherosclerotic occlusive disease were divided into a control group and an observation group with 55 cases each according to the admission time to the hospital.Both groups were treated with alprostadil and then Xueshuantong was additionally given in the observation group.The ankle-brachial index(ABI)and toe-brachial index(TBI)indices,hemodynamic indexes,the incidence of adverse reactions and the effective rate of the treatment were compared between the two groups before and after the treatment.Results:After treatment,the treatment efficiency,ABI and TBI indexes were higher and the hemodynamic indexes and the incidence of adverse reactions were lower in the observation group than the control group(all P<0.05).Conclusion:Xueshuantong combined with alprostadil for the treatment of lower limb atherosclerotic occlusive disease has exact clinical efficacy and can effectively improve the hemodynamic indexes and the quality of life of the patients.
关键词
血栓通/前列地尔/下肢动脉硬化闭塞症Key words
Xueshuantong/alprostadil/lower limb atherosclerotic occlusive disease引用本文复制引用
出版年
2024
NETL
NSTL
万方数据