腹腔镜辅助胃癌根治术患者肿瘤异常蛋白、胃癌相关抗原水平变化与复发转移的相关性
Correlation between the changes of tumor abnormal protein and gastric cancer-related antigen and the recurrence and metastasis of cancer in patients undergoing laparoscopic-assisted radical gastrectomy
刘紫朦 1赵传稳 1余昌达 1叶琳1
作者信息
- 1. 九江市第一人民医院普外一科 九江 332000
- 折叠
摘要
目的:探讨腹腔镜辅助胃癌根治术患者肿瘤异常蛋白(TAP)、胃癌相关抗原MG7-Ag水平与肿瘤复发转移的相关性.方法:选择 110 例行腹腔镜辅助根治术的胃癌患者,随访 12 月后分为复发转移组(n=37)和无复发转移组(n=73),另招募同期 55 例体检健康者为健康组.比较术前、术后TAP、MG7-Ag水平,采用Pearson分析TAP、MG7-Ag水平与肿瘤复发转移的相关性.结果:复发转移组术前、后TAP、MG7-Ag水平高于无复发转移组;TAP、MG7-Ag水平与胃癌患者根治术后肿瘤复发转移呈正相关(r=0.654,0.579,P＜0.005).结论:TAP、MG7-Ag水平变化可评估腹腔镜辅助胃癌根治术患者肿瘤复发转移情况.
Abstract
Objective:To discuss correlation between the change of tumor abnormal protein(TAP)and gastric cancer-related antigen MG7-Ag levels and the recurrent metastasis of cancer in patients undergoing laparoscopic-assisted radical gastrectomy.Methods:One hundred and ten patients with gastric cancer who underwent laparoscopic-assisted radical surgery were selected and divided into a recurrent metastasis group(n=37)and a no recurrent metastasis group(n=73)12-monthes after follow-up,and meanwhile another 55 healthy patients with physical examination were recruited as a healthy group.The pre-and post-operative TAP and MG7-Ag levels were compared,and the correlation between the TAP and MG7-Ag levels and the recurrent metastasis of tumor was analyzed by Pearson.Results:The pre-and post-operative TAP and MG7-Ag levels were higher in the recurrent metastasis group than the no recurrent metastasis group and TAP and MG7-Ag levels were positively correlated with the recurrent metastasis of tumor after radical surgery in gastric cancer patients(r=0.654,0.579,P<0.005).Conclusion:The change of TAP and MG7-Ag levels can be used for the assessment of the recurrent metastases of tumor in patients undergoing laparoscopic-assisted radical gastrectomy.
关键词
腹腔镜辅助胃癌根治术/肿瘤异常蛋白/胃癌相关抗原/复发转移Key words
laparoscopic-assisted radical gastrectomy/tumor abnormal protein/gastric cancer-related antigen引用本文复制引用
出版年
2024
NETL
NSTL
万方数据