Clinical pharmacist participates in the pharmacological monitoring of anti-infective therapy in a patient with cirrhosis complicated with Mycoplasma pneumoniae pneumonia
A patient with liver cirrhosis complicated with Mycoplasma pneumoniae pneumonia had poor effect on azithromycin to control the infection and the clinical pharmacist recommended to adjust to levofloxacin considering the factors such as bacterial resistance and the patient's pathophysiology and so on.The resistance rate of azithromycin to adult community-acquired Mycoplasma pneumoniae in China is high,while azithromycin may increase the risk of acute liver injury and mortality in patients with liver cirrhosis.Levofloxacin may be one of the drugs of choice for Mycoplasma pneumoniae pneumonia in adults and the patients with decompensated liver function do not require dosage reduction.
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