The effect of lyophilized essence of compound traditional Chinese medicine extracts on scalp tissue aging
Objective:To explore the effects of lyophilized essence of compound traditional Chinese medicine extracts on scalp tissue aging.Methods:Normal human scalp tissues cultured in vitro were selected as the experimental subjects,which were divided into a control group and an extracts essence treatment group.The tissues were cultured in William's complete medium,and the effects of the extracts essence on the key proteins associated with scalp aging were evaluated by enzyme-linked immunosorbent assay and immunofluorescence detection.Results:In scalp tissues cultured in vitro,the extracts essence could significantly reduce the expression level of interleukin 6 to below 1%of the baseline at the concentrations of x/5,x/3,and x/2.In addition,the extracts essence could decrease the expression levels of 8-hydroxy-2'-deoxyguanosine(8-OHdG)by 25%,versican by 48%and myelin protein zero-like 3(MPZL3)by 19%at a concentration of x/10(all P<0.01),and the expression of 8-OHdG by 24%,versican by 24%and MPZL3 by 33%at a concentration of x/5(all P<0.01),respectively.Conclusion:The lyophilized essence of compound Chinese medicine extracts has anti-inflammatory,antioxidant and anti-aging effects on human scalp tissues cultured in vitro and a value of further clinical research.
lyophilized essence of compound Chinese medicine extractsscalp tissueanti-aging
NETL
NSTL
万方数据
