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通窍平鼾方治疗小儿腺样体肥大(肺脾气虚证)的疗效观察

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目的:探讨通窍平鼾方治疗肺脾气虚型小儿腺样体肥大疗效.方法:将 102 例腺样体肥大(肺脾气虚型)患儿随机分为观察组(n=51)和对照组(n=51),对照组接受常规西医治疗,观察组联合通窍平鼾方治疗.治疗 1个月后,比较 2 组临床疗效、复发率、中医证候积分、腺样体体积积分、血清过敏原特异性IgE(sIgE)、炎症指标及生活质量(OSA-18 评分).结果:观察组治疗后各项中医证候积分、腺样体体积积分、sIgE指标、TNF-a、IL-6 指标、OSA-18 评分、复发率均低于对照组(P<0.05);IL-10 指标、总有效率均高于对照组(P<0.05).结论:通窍平鼾方能够降低腺样体肥大患儿血清sIgE水平,缩小腺样体体积,调节炎症指标水平,改善预后.
Observation on the therapeutic effect of Tongqiao Pinghan formula in the treatment of pediatric adenoid hypertrophy(lung and spleen Qi deficiency syndrome)
Objective:To investigate the efficacy of Tongjiao Pinghan formula in the treatment of adenoid hypertrophy in children with lung and spleen Qi deficiency type.Methods:One hundred and two children with adenoid hypertrophy(lung and spleen Qi deficiency type)were randomly divided into an observation group(n=51)and a control group(n=51).The control group received conventional Western medical treatment,and the observation group was treated with Tongqiao Pinghan formula.The clinical efficacy,recurrence rate,TCM symptom score,adenoid volume score,serum allergen-specific IgE(sIgE)level,inflammation index and quality of life(OSA-18 score)were compared between the two groups after 1 month of treatment.Results:The TCM symptom score,adenoid volume score,sIgE index,TNF-a,IL-6 index,OSA-18 score,and recurrence rate were lower and IL-10 index and total effective rate were higher in the observation group than the control group after treatment(P<0.05).Conclusion:Tongqiao Pinghan formula can reduce the serum sIgE level and the volume of adenoids in children with adenoid hypertrophy,regulate the level of inflammatory indicators,and improve the prognosis.

pediatric adenoid hypertrophyTongqiao Pinghan formulalung and spleen Qi deficiency syndromesIgEinflammation indicator

唐汝宁、王婷婷

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驻马店市中医院儿科 驻马店 463000

小儿腺样体肥大 通窍平鼾方 肺脾气虚证 sIgE 炎症指标

2024

上海医药
上海医药行业协会

上海医药

影响因子:0.781
ISSN:1006-1533
年,卷(期):2024.45(13)