Effects of DP chemotherapy regimen combined with Kanglaite injection on immune function and angiogenesis indexes in patients with lung adenocarcinoma
Objective:To investigate the effect of docetaxel plus cisplatin(DP)chemotherapy regimen combined with Kanglaite injection in the treatment of patients with lung adenocarcinoma.Methods:Ninety-two patients with lung adenocarcinoma were randomly divided into a control group and an observation group with 46 cases each.The control group was treated with DP chemotherapy,while the observation group was additionally treated with Kanglaite injection,and all the treatments were lasted for two cycles.The treatment effect,immune function,angiogenesis indexes and incidence of adverse reactions were compared between the two groups.Results:After treatment,the disease control rate,CD3+,CD4+levels,CD4+/CD8+value were higher and the levels of CD8+,vascular endothelial growth factor A,basic fibroblast growth factor and the incidence of adverse reactions were lower in the observation group than the control group(P<0.05).Conclusion:DP chemotherapy regimen combined with Kanglaite injection for the treatment of lung adenocarcinoma is satisfactory and can regulate the immune function and angiogenesis indexes and has good safety.
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