Clinical research on modified Tianma Gouteng decoction and Shengjiang powder in the treatment of acute cerebral infarction(wind-fire disturbance syndrome)
Objective:To investigate the clinical efficacy of the modified Tianma Gouteng decoction and Shengjiang powder in patients with acute cerebral infarction(ACI)(wind-fire disturbance syndrome).Methods:Seventy cases of patients with wind-fire upper disturbance syndrome of ACI(wind-fire disturbance syndrome)were retrospectively analyzed and were divided into an observation group(n=35)and a control group(n=35)according to the different treatments.All the patients received conventional treatments,and the observation group was additionally treated with the modified Tianma Gouteng decoction and Shengjiang powder,and the treatments was lasted for a month.NIHSS scores,immunological indexes,serum D-dimer level and erythrocyte sedimentation rate(ESR),hypersensitive C-reactive protein(hs-CRP)level were compared between the two groups before and after treatment,and clinical efficacy was also compared.Results:After treatment and at follow-up,NIHSS score,NK cell proportion,CD8+proportion,serum D-dimer,ESR and hs-CRP levels were lower and CD4+proportion and CD4+/CD8+ratio were higher in the observation group than the control group(all P<0.05).NK cell proportion and CD8+proportion of the patients in the two groups were significantly higher at the follow-up than the post-treatment,and CD4+/CD8+ratio was significantly lower after treatment(all P<0.05).The recovery rate of the observation group was higher than that of the control group(60.00%vs 22.86%,P<0.05).Conclusion:On the basis of conventional treatment for ACI(wind-fire disturbance syndrome),the addition of the modified Tianma Gouteng decoction and Shengjiang powder can significantly improve the state of neurological deficits and the clinical efficacy is better.
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