Objective:To explore the value of the application of transcranial Doppler(TCD)in monitoring cerebral vasospasm(CVS)after intervention for ruptured cerebral aneurysm.Methods:A total of 80 patients who underwent intervention for ruptured cerebral aneurysm were selected.TCD was monitored preoperatively and postoperatively to assess blood flow velocities in the middle cerebral artery and intracranial segment of the internal carotid artery,and examination was performed by digital subtraction angiography(DSA).The diagnostic value of TCD for CVS was evaluated with DSA results as reference.Results:Blood flow velocity in the middle cerebral artery increased in 1-14 days after surgery compared with before surgery,in which it was higher day 3-7 than day 1 after surgery,followed by a gradual decrease at day 10-14.Blood flow velocity in the intracranial segment of the internal carotid artery was lower day 3-10 than day 1 after surgery,but higher on day 10 than day 7.Forty-two cases of CVS and 38 cases of non-CVS were confirmed by DSA.The blood flow velocity of the middle cerebral artery in the CVS group was higher than that in the non-CVS group at day 1-14 after surgery(P<0.05).The accuracy of TCD diagnosed by CVS was 86.25%,with a sensitivity of 80.95%,specificity of 92.11%,positive predictive value of 91.89%,and negative predictive value of 81.40%.The consistency between TCD and DSA results was good(Kappa=0.726).The symptoms of CVS patients were improved after treatment with nimodipine,the blood flow in middle cerebral artery was returned to normal,and there was no case of hemiparesis or death.Conclusion:TCD can monitor the changes of blood flow velocity in middle cerebral artery after intervention for ruptured cerebral aneurysm and can provide a reliable basis for the clinical diagnosis of CVS.
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