Efficient synthesis of 1,4-dihydropyridines catalyzed by microwave and ionic liquids
2,6-dimethyl-4-3'-nitrophenyl-N3,N5-diphenyl-3,5-diformamide dihydropyridine was synthesized from 3-nitrobenzaldehyde,3-oxygen-N-phenylbutanamide and ammonium acetate via Hantzsch reaction in the presence of ionic liquid with pyridine as the mother under microwave irradiation.The corresponding structure of the product is characterized by 1H-NMR.Compared by the methods in the literature,this method has a simple reaction process,short reaction time,high yield,and easy reuse.
Hantzsch reactionionic liquidmicrowave irradiationone pot
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