世界复合医学2024,Vol.10Issue(3) :109-112.DOI:10.11966/j.issn.2095-994X.2024.10.03.28

增液承气汤联合乳果糖治疗肿瘤患者化疗相关性便秘的临床价值分析

Clinical Value of Zengye Chengqi Decoction Combined with Lactulose in the Treatment of Chemotherapy-related Constipation in Tumor Patients

李玲玲 朱建军
世界复合医学2024,Vol.10Issue(3) :109-112.DOI:10.11966/j.issn.2095-994X.2024.10.03.28

增液承气汤联合乳果糖治疗肿瘤患者化疗相关性便秘的临床价值分析

Clinical Value of Zengye Chengqi Decoction Combined with Lactulose in the Treatment of Chemotherapy-related Constipation in Tumor Patients

李玲玲 1朱建军1
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作者信息

  • 1. 盐城市亭湖区人民医院肿瘤科,江苏盐城 224002
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摘要

目的 分析化疗相关性便秘的肿瘤患者应用增液承气汤联合乳果糖的效果及对便秘症状的影响.方法 便利选取2020年3月—2023年3月盐城市亭湖区人民医院收治的66例恶性肿瘤化疗后便秘患者作为研究对象,用随机数表法分为对照组和观察组,各33例.对照组予以乳果糖治疗,观察组予以增液承气汤+乳果糖治疗,治疗1周后评估效果.结果 治疗1周后,两组患者Bristol粪便性状评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05).治疗1周后,两组患者便秘症状评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05).两组患者治疗总有效率比较,差异无统计学意义(P>0.05).观察组痊愈率高于照组,差异有统计学意义(χ2=4.062,P=0.044).结论 对于肿瘤化疗后便秘患者,增液承气汤,联合乳果糖能够取得显著临床疗效,促进便秘症状的改善.

Abstract

Objective To analyze the effect of Zengye Chengqi Decoction combined with lactulose on chemotherapy-related constipation in tumor patients and its effect on constipation symptoms.Methods A total of 66 patients with constipation after chemotherapy for malignant tumors admitted to Tinghu District People's Hospital from March 2020 to March 2023 were conveniently selected as the study objects,and were they di-vided into control group and observation group by random number table method,with 33 cases in each group.The control group was treated with lactulose,the observation group was treated with Zengye Chengqi decoction+lactulose,and the effect was evaluated after 1 week of treatment.Results After 1 week of treatment,the Bristol fecal trait score in two groups of patients was higher than before treatment,and the observation group was higher than that in control group,and the differences were statistically significant(P<0.05).After 1 week of treatment,the score of constipation symptom in 2 groups was lower than before treatment,and the observation group was lower than that in control group,and the differences were statistically significant(P<0.05).There was no signifi-cant difference in the total effective rate between the two groups of patients(P>0.05).The recovery rate of obser-vation group was higher than that of control group,and the difference was statistically significant(χ2=4.062,P=0.044).Conclusion The combination of Zengye Chengqi Decoction and lactulose for patients with constipation after tumor chemotherapy can achieve significant clinical effect and promote the improvement of constipation symptoms.

关键词

化疗相关性便秘/乳果糖/增液承气汤/临床效果

Key words

Chemotherapy-related constipation/Lactulose/Zengye Chengqi Decoction/Clinical effect

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出版年

2024
世界复合医学

世界复合医学

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