Objective To analyze the effect of the treatment of cerebral infarction with Buyang Huanwu de-coction+Xuesaitong injection.Methods A total of 80 patients with cerebral infarction admitted to Qianxi People's Hospital from January 2023 to January 2024 were simple randomly selected and divided into control group and study group with 40 cases each by odd and even grouping method.The control group was treated with Xuesaitong injection and the study group was treated with Buyang Huanwu decoction and xuesaitong injection.The blood lipid indexes,outcome,effective rate and adverse reactions of the two groups were compared.Results After treatment,triglyceride and total cholesterol in the study group were lower than those in the control group,and high-density lipoprotein cholesterol was higher than those in the control group,and the differences were sta-tistically significant(all P<0.05).After treatment,the outcomes of the study group was lower than that of the con-trol group,and the difference was statistically significant(all P<0.05).The treatment effective rate of the study group was 97.50%,which was higher than that of the control group 80.00%,and the difference was statistically significant(χ2=6.135,P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion The combination of Buyang Huanwu decoction and Xuesaitong can enhance the efficacy,continuously reduce the blood lipid level,reduce the degree of nerve damage,and the overall safety is high,which can restore the self-care ability of patients with cerebral infarction.